Note that using her Standard Skill and dodge cause Clarina to lose 20% of her current HP.
Clarina thus loses more HP the more HP she has, whereas her healing is fixed.
This means Clarina tends to gain a lot of HP when low on HP, and tends to on-average lose a little HP when her HP is full.
Mathematically, with no external healing, Clarina's Standard Skill healing of 3,960 means that Clarina's HP will asymptote to 19,800 whilst she is spamming her Standard Skill.
If she has more HP than that, she will on-average lose HP.
If she has less HP than that, she will on-average gain HP.
If you just spam her Standard Skill continuously, her HP will oscillate around that number.
At Lvl.80, Clarina has a max base HP of 22,911, which after factoring in her Logistics bonus puts her at 27,493 HP, which is very low, especially for a main DPS.
With maxed Manifestations, Clarina has a max HP of 28,867, which is again, quite low for a main DPS.
Clarina does gain Max HP from her Deiwos, but overall her HP is still quite low.
Despite this, at Lvl.80 Clarina has a base DEF of 1,272, which is very high. With the 20% Logistics bonus, Clarina has 1,526 DEF, which is extremely high.
As such, Clarina tends to have low-ish HP but high DEF.
Her high DEF combined with her self-healing does make her much more bulky than a typical operative.
Clarina's high DEF, very high self-healing potential, and high mobility means that Clarina generally has the most survivability of any operative in the game, by a notable margin.
Obviously you can give any other operative strong survivability by having them supported by a healer (i.e. Eatchel), but when played solo, Clarina is in a league of her own.
Having to rely on her high DEF and the average of her self-healing does make Clarina very vulnerable to effects that reduce DEF and/or self-healing.
Having either such effect can be a huge nerf to Clarina's survivability.
Note that some effects that reduce how much healing Clarina gets can cause her HP to drop quite quickly by using her standard skill, leading to extremely low survivability.
For example in Underground Purge there is a -50% Healing effect, which makes Clarina mostly unplayable, as she just takes so much damage and can't really heal herself, which makes her incredibly fragile.